The Italian champions will be looking to extend their lead in Serie when they travel to the Stadio Artemio Franchi.
Juventus will rate their chances of obtaining their sixth victory of the season when they clash with a beleaguered Siena on Sunday.

La Vecchia Signora have been in outstanding form in the Serie A so far this season, and are expected to rack up another three points against highly-vulnerable opponents.

Antonio Conte's men thumped Roma 4-1 last weekend, and want to continue to take advantage of the difficulty experienced by their most likely title candidates.

While Napoli have been in good form this season, other potential title contenders like Roma, Inter and AC Milan have struggled enormously.

Juventus, who were held to a 1-1 draw by Shakhtar Donetsk in the Champions League midweek, understand that participating in Europe's maximum club competition could lead to more injuries for their squad members than last season and for that reason will take precaution.

Coach Antonio Conte is expected to rotate his squad, and this means that playmaker Antonio Pirlo will be replaced by Paul Pogba. Meanwhile, Stephan Lichtsteiner and Leonardo Bonucci will be replaced by Mauricio Isla and Luca Marrone, respectively.

While Conte has practically confirmed his starting eleven, he has yet to decide who will partner Mirko Vucinic in the attack. His possible options include Alessandro Matri, Fabio Quagliarella and Sebastian Giovinco.

Meanwhile, Siena coach Serse Cosmi will have to make do without key midielder Gaetano D'Agostino. However, Alessandro Rosina is expected to boost his attack.

In the corresponding fixture last season, Juventus scraped past their rivals 1-0 with a strike from Matri. But the last time the teams met in February they fought out a goalless stalemate.