Cruzeiro, main favorite for the Libertadores title, host Once Caldas as reigning champion Internacional take on Peñarol.
Velez Sarsfield, Fluminense, Cruzeiro, Universidad Catolica and Santos want to confirm last week's victory to advance to the fourth round of the Copa Libertadores. Gremio and Internacional are the only Brazilian squads that failed to celebrate a victory in the first-leg match of the knockouts.

Two of the hottest matches of the round of sixteen (Estudiantes vs Cerro Porteño and Peñarol vs Internacional) ended up in a tie. Four of the most experienced contenders in the Libertadores chance their arms in the struggle for the American glory.

Velez Sarsfield must stop LDU Quito from scoring three or more goals in Liniers to secure their ticket to the next round. The Argentineans will most likely be facing Fluminense in the quarter-finals, as the Brazilians rescued an important and sound victory 3-1 against Libertad in Paraguay.

America and Jaguares, the only two Mexican squads that made it this far in the competition, have to s
 

Gremio visits Chile with a decimated squad, eager to recover from last week's defeat in Porto Alegre. Gremio's Fabio Rochemback, André Lima, Willian Magrão, Lucio, goalkeeper Victor and winger Gabriel are missing this clash due to injuries. Damian Escudero, on the other hand, is likely to return to the starting eleven.





Universidad Catolica's Argentinean striker Lucas Pratto has become one of the main revelations of the tournaments, having already score six goals in 7 Libertadores games.





No other Brazilian squad is as compromised as Gremio to make it to the quarter-finals. Universidad Catolica remains unbeaten playing away, and in the three games they've played as visitors, the Chileans have already scored eight goals.





The winner faces a highly experienced rival in the quarter finals, either reigning champion Internacional or Peñarol. A victory is mandatory to reach such a decisive game with the best possible momentum.





A vital clash for the American glory, who'll be victorious?



America hosts Santos this Tuesday 160 milles away from the Aztec stadium, performing at Querataro's La Corregidora. The Mexicans had to change the location of the game as U2, the Irish rock band, features at the Estadio Azteca in the next days.





America's coach Carlos Reinoso lead the team towards an important victory last weekend against Pumas for the Mexican league, and is confident his Eagles can stop Santos from reaching the quarter-finals. America finished at the top of the third group with 10 points.





The Mexican offensive trident (Ángel Reyna, Rosinei, Vicente Sanchez) will clash against the irregular Brazilian defense. Muricy Ramalho misses Brazilian international Elano, who made way to Adriano in the starting eleven due tu a muscular fatigue.





It's the third clash between America and Santos in the Knockouts. The Brazilians advanced to the semi-finals back in 2007, and a year later the Mexicans claimed their place in the semi-finals.



The champion must secure a positive result against Peñarol to claim a place among America's Best Eight. Internacional's coach Roberto Falcao prepares a highly offensive squad to shatter Peñarol's dreams of reaching the quarter-finals.





Los Carboneros managed to stop Internacional from celebrating a victory in Uruguay last week, but it might not be enough to advance to the next round.





Peñarol's coach Diego Aguirre recovers strikers Juan Manuel Olivera and Jhonatan Urretaviscaya, who missed the first game against Internacional due to disciplinary action and injuries respectively.





Internacional recovers midfielder Mario Bolatti, who could be joining either Pablo Guiñazu or Tinga in the creative department.





Can Internacional defend the title against Peñarol this Wednesday in Belo Horizonte?



Juan Carlos Osorio's Once Caldas must visit Brazil to lock horns with one of the deadliest squads in the fight for America's most coveted title. The Colombians were defeated by Cruzeiro 2-1 last week at Manizales.





Out of Once Caldas' five visits to Brazil, the Colombian squad has never been able to celebrate a victory. The visitors need to score at least two goals to jeopardize Cruzeiro's qualification.





Juan Carlos Osorio recovers wingers Elkin Calle and Luis Núñez, unable to perform in the first clash due to injuries.





Cruzeiro's striker Thiago Ribeiro misses the game due to injuries, and team's top striker Wallison could be unable to perform as well as he struggles with a knee injury.





A clash of epic proportions takes place at the Beira Rio... Who'll succeed?



Libertad was defeated for the first time in the Libertadores last week in Rio de Janeiro, and the Paraguayans must defeat Fluminense by at least two goals to remain competitive in the fight for qualification.





Both Libertad and Fluminense tied their last game 1-1, the Paraguayans against Tacuary and Fluminense facing Flamengo in their respective domestic leagues.





"We must be intelligent, because our rival has strengths of its own. We have our feet on the ground, but we still believe we can make it" said Libertad's coach Gregorio Perez.





Argentinean midfielder Sergio Aquino returns to Libertad's starting eleven, and he will most likely be taking over Rodrigo Rojas' place.





Fluminense's coach Anderson Moreira trusts Fred and Rafael Moura the attack of the Brazilian squad. Can Libertad stop Fluminense from reaching the quarter-finals.



Cerro Porteño wants to secure their ticket to the Quarter-Finals this Thursday in Asuncion. Leo Astrada's Cerro rescued an important draw from last week's visit to La Plata.





Pedro Benitez and Iván Piris are ruled out doe to injuries, and this greatly undermines Cerro's defenisve strength.





The Argentinean squad suffered a major defeat last weekend in Liniers facing Velez Sarsfield for the local Clausura. Pincha's coach Eduardo Berizzo is aware a victory is mandatory for Estudiantes to recover its spirit and secure the qualification.





Estudiantes' coach misses playmaker Juan Sebastian Veron, who is sidelined with influenza. Raul Iberbia, on the other hand, is likely to return to the starting eleven, joining Hernan Rodrigo Lopez and Gaston Fernandez in the attack.





Cerro Porteño and Estudiantes take on each other, and the winner takes all. Who'll be victorious?


LDU Quito depends on a miracle to claim a place in the quarter-finals, as Velez's extraordinary performance last week in Liniers (They celebrated a 3-0 victory over Liga) granted the Argentinean squad half a ticket to join America's Top Eight squads.





Ricardo Gareca's Fortineros are going through an excellent moment, as they've shown last weekend in the Clausura by soundly defeating Estudiantes 4-1.





The Ecuadorian powerhouse misses team's captain Neicer Reasco, as well as Luis Bolaños. Playmaker Miller Bolaños, on the other hand, is likely to return to the starting eleven.





LDU Quito's coach Edgardo Bauza will have to find a way to stop Velez's offensive trident (Maximiliano Moralez, Juan Manuel Martinez and Santiago Silva) or will otherwise be doomed to a 90-minute long nightmare at the Casa Blanca.





The Ecuadorians have not lost a single point at home so far in the Libertadores, scoring 10 goals in three Libertadores games while conceding none.





Two true candidates for the Libertadores struggle for a place in the quarter-finals. Can the hosts stop Velez Sarsfield from confirming its superiority?


"Junior is an excellent rival. I'm proud that I've always scored a goal against them, back in Medellin and now with Jaguares. I hope this won't be the first exception" said Jaguares' striker Jackson Martinez.





Junior can secure a ticket to the next round by keeping its goal shut this Thursday at Barranquilla. The Colombians were one of the deadliest squads in the Group Stage, but they have yet failed to show the same determination in the knockouts.





the experience of Junior' top striker Carlos Bacca will be one of Oscar Quintabani's main weapons to secure qualification.





Team's coach trusts Giovanni Hernandez to lead the attack, feeding César Fawccet and Jossymar Rodríguez on the wings to overwhelm Jaguares.





The winner advances to the quarter-finals to take on with either Estudiantes or Cerro Porteño, two highly offensive rivals. Can Junior Barranquilla make the Metropolitano Roberto Meléndez its fortress and stop the Mexican squad from reaching the next stage?