Matchday 25 will give English Premier League fans around the world a chance to witness some interesting matches, including one where José Mourinho and Pep Guardiola will reignite their historic rivalry.
Elsewhere, the record-breaking team led by Jürgen Klopp will try to keep their unbeaten form when they host Southampton. Ralph Hassenhüttl's men have shocked one or two teams this season, and Klopp's crew must be wary to avoid any surprises.
One more game that could be quite interesting to watch will be Wolves' visit to Old Trafford. Nuno's men are still in contention for a UEFA Champions League spot, and they will surely try to mess Bruno Fernandes' potential debut with the Red Devils.
Without further ado, here's what you need to keep an eye on for Matchday 25 in the English Premier League.
Team news - Who's in, who's out?
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Arsenal - Injured: Shkodran Mustafi, Kieran Tierney, Calum Chambers, Reiss Nelson, Sead Kolasinac.
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Chelsea - Injured: Marco Van Ginkel, Christian Pulisic. Doubtful: Ruben Loftus-Cheek, Reece James, Tammy Abraham, Olivier Giroud.
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Leicester City: Injured: Daniel Amartey, Nampalys Mendy. Doubtful: Matty James.
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Liverpool - Injured: Nathaniel Clyne, Sadio Mané. Doubtful: Adam Lallana, James Milner, Xherdan Shaqiri, Divock Origi.
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Manchester City - Doubtful: Leroy Sané, Aymeric Laporte, Fernandinho, Benjamin Mendy.
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Manchester United - Injured: Marcus Rashford, Paul Pogba, Scott McTominay, Axel Tuanzebe. Doubtful: Timothy Fosu-Mensah. Suspended: Nemanja Matic.
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Tottenham Hotspur - Injured: Ben Davies, Harry Kane, Moussa Sissoko, Tanguy Ndombele.
Coach's quotes ahead of Matchday 25
Bruno Fernandes' signing for Manchester United stole most headlines during the winter, and finally, the Portuguese playmaker made his way to Old Trafford. Speaking at the player's unveiling ceremony, coach Ole Gunnar Solskjaer named a few of his new player's skills that will come in handy for the Red Devils during the rest of the season.
"The winter break is coming at a perfect time for us to integrate Bruno into the squad and for him to get to know his team-mates. Bruno's goals and assists stats speak for themselves, he will be a fantastic addition to our team and he will help us push on in the second part of the season," Solskjaer stated.
Key historical stats ahead of the EPL's Matchday 25
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Liverpool have won each and every one of their last 19 Premier League games at home.
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Arsenal has drawn their last four away games (Premier League).
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Manchester United has won seven of their last eight games against Wolves at home (all comps).
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Leicester enters this game on a three-match streak without a loss against Chelsea (all comps).
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Manchester City has won four out of their last five Premier League games.
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This will be the 23rd meeting between Pep Guardiola and Jose Mourinho. Manchester City's boss has won eleven games, while Mourinho has only been able to win five times against the Catalan coach.
English Premier League - Matchday 25 games
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