Second placed Norwich City will be looking to extend a seven game unbeaten streak when they travel to face Hull City on Saturday.
League leading Queens Park Rangers will also be in action and could extend their seven point lead at the top of the table with a win at struggling Doncaster Rovers.
All four occupants of the playoff spots will also be in action on Saturday. Swansea City and Nottingham Forest will go head to head, while Cardiff City and Leeds United will travel to face Millwall and Sheffield United respectively.
At the bottom end of the table, last placed Preston North End will play host to slumping Coventry City, while Scunthorpe United will face Ipswich Town at Portman Road.
Crystal Palace will be hoping to pull clear of the bottom three with a win over Derby County.
Relegation threatened Sheffield United will play host to promotion chasing Leeds United in the early kickoff on Saturday.
The Blades are currently in the relegation zone six points adrift of safety, while Leeds currently occupy the playoff zone. Leeds are the Championship’s leading goal scorers, while the Blades have scored less than any team in the division.
Blades duo Darius Henderson and Lee Williamson are suspended, while Johnny Ertl is ruled out with a knee problem. Matt Lowton is an injury doubt, while Bjorn Helge Riise is set to return from a hamstring strain.
Defender Paul Connolly will return for Leeds after a long injury layoff, while captain Richard Naylor should also be fit to play.
Playoff chasing Burnley will continue their promotion challenge when they travel to face Bristol City on Saturday. Burnley are three points behind sixth placed Nottingham Forest with a game in hand, while Bristol are 10 points further back.
Burnley will be looking to extend a four game unbeaten run away from home, while Bristol will be looking for their third straight home win.
Defender Liam Fontaine looks set to miss out for an ankle injury for Bristol. Even if he manages to face Burnley, Fontaine is likely to undergo season ending surgery next week.
Dean Marney is doubtful for Burnley with a knee problem and will be assessed ahead of kickoff. Charlie Austin, Steven Thompson, Martin Paterson and Chris McCann are all ruled out with injury for the Clarets.
Cardiff City will continue their promotion challenge when they travel to face mid-table Millwall on Saturday. Cardiff are four points behind second placed Norwich City and will be looking to snap a three game winless skid. Millwall are seven points behind the playoff spots and will be looking for their third straight win.
Defender Darren Purse is back from suspension for Millwall, while striker Neil Harris will return from a hip injury. Midfielder Hameur Bouazza could also feature for the Lions after recovering from a knee problem.
Striker Michael Chopra is ruled out for Cardiff with a torn hamstring, while goalkeepers Tom Heaton and David Marshall remain sidelined with injury.
Rock bottom Preston North End will play host to Coventry City having snapped a 15 game winless streak in midweek. Preston’s 3-0 win at Scunthorpe United means they are now 10 points adrift of safety, while Coventry are eight points above the drop zone after a six game winless streak.
PNE have no fresh injury concerns, and manager Phil Brown looks set to field the same team that earned him his first win as manager in midweek.
Striker Marlon King is suspended for Coventry, while Martin Cranie is ruled out with a hamstring injury. Clive Platt and Lee Carsley are injury doubts and will be assessed ahead of kickoff.
Swansea City and Nottingham Forest will go head to head in a promotion battle at the Liberty Stadium. Third placed Swansea are three points behind the automatic promotion spots, while sixth placed Forest are three points further back.
Both teams will enter this game looking to regain their winning touch. Forest are without victory in their last six games, while Swansea are winless in three.
Striker Fabio Borini could make his Swansea debut after joining the club this week on loan from Chelsea. Captain Garry Monk and Andrea Orlandi could return from injury for the Swans.
Forest striker Robert Earnshaw has been ruled out for month with a hamstring injury, while Middlesbrough loanee Kris Boyd could make his full debut in the Forest attack.
League leading Queens Park Rangers will be looking to extend their seven point lead at the top of the table when they travel to face struggling Doncaster Rovers.
QPR have won four of their last five games, while Doncaster have slid to within 10 points of the relegation zone after one win on their last 10 fixtures.
John Oster and Neil Sullivan will return from injury for Rovers, while leading goal scorer Billy Sharp is out due to a groin problem. Joe Mills, James Chambers, James O’Connor and Mustapha Dumbaya will all be sidelined with injury for Doncaster.
Reading will be looking to extend a six game Championship unbeaten streak when they travel to face Barnsley on Saturday.
Reading are six points behind sixth placed Nottingham Forest with a game in hand, while Barnsley are a further seven points back.
Midfielder Hugo Colace could feature for Barnsley after along injury layoff that included rumors of him leaving the club. Jacob Mellis, Paul McShane and Jason Shackell are all injury doubts and will be assessed ahead of kickoff.
Reading’s Matt Mills is ruled out with injury along with Ivar Ingimarsson, Alex Pearce and Andy Griffin. Mikele Leigertwood, Noel Hunt and Jobi McAnuff are all doubtful and will be assessed ahead of kickoff.
Relegation threatened Scunthorpe United will be looking to avoid their fourth straight defeat when they travel to face Ipswich Town at Portman Road.
Scunthorpe currently occupy the relegation zone and are four points adrift of safety, while Ipswich are 12 points above the bottom three after a three game winless streak.
Ipswich captain David Norris is out with an ankle problem, while Mark Kennedy is a long-term injury absentee. Colin Healy could feature for the Tractor Boys after recovering from a stomach problem.
Sam Togwell and Ben Gordon will return from injury for Scunthorpe, while Andy Hughes could also be sidelined.
Leicester City and Portsmouth will go head to head with both teams looking for points to keep their playoff hopes alive. Leicester are five points behind sixth placed Nottingham Forest, while Portsmouth are four points further back.
Chelsea loanee Jeffrey Bruma could return for Leicester, while Steve Howard and Patrick van Aanholt are sidelined with injury for the Foxes.
Former Portsmouth striker Yakubu Ayegbini will lead the Leicester attack against a Pompey team that has kept clean sheets in seven of their last eight games.
Midfielder Liam Lawrence is doubtful for Portsmouth after aggravated a calf injury in training this week.
Playoff chasing Watford will be looking to extend a five game winning streak when they travel to face struggling Middlesbrough. Watford are currently four points behind the playoff spots, while Middlesbrough are seven points above the drop zone after going unbeaten in their last two games.
Defensive pair Stephen McManus and Andrew Davies are injury doubts for Middlesbrough, with Maximilian Haas and Jonathan Grounds being possible replacements.
Boro also have lack of attacking options with Leroy Lita injured and Kris Boyd and Lee Miller currently out on loan.
Middlesbrough fans will rue the fact that Championship leading goal scorer Danny Graham who will lead Watford’s attack is a graduate of the Middlesbrough youth academy, and left the club with few people noticing four years ago.
Defensive due Lloyd Doyley and Lee Hodson are injury doubts for Watford and will be assessed ahead of kickoff.
Crystal Palace will be hoping to pull clear of the relegation zone when they play host to Derby County on Saturday. Palace are currently four points clear of the bottom three, while Derby are five points further ahead after a morale boosting win over promotion chasing Swansea City last weekend.
Defender Claude Davis could start for Palace against his former club, while Paddy McCarthy (suspension) and Alex Marrow (injury) will miss out for the Eagles.
Tomasz Cywka is sidelined for Derby with a knee problem, while Jake Buxton (groin) and Shaun Deeney (shoulder) are also ruled out. Russell Anderson and James Bailey look set ot return to fitness for the Rams.
Second placed Norwich City will be looking to extend a seven game unbeaten streak when they travel to face Hull City on Saturday. Norwich are three points ahead of third placed Swansea City, while Hull are five points behind the playoff spots.
Defender Andy Dawson looks set to return for Hull, while Hope Akpan will make his Tigers debut after joining the club this week from Everton.
Chris Martin is ruled out with a hamstring injury for Norwich, while Aaron Wilbraham is doubtful with a back problem.
All four occupants of the playoff spots will also be in action on Saturday. Swansea City and Nottingham Forest will go head to head, while Cardiff City and Leeds United will travel to face Millwall and Sheffield United respectively.
At the bottom end of the table, last placed Preston North End will play host to slumping Coventry City, while Scunthorpe United will face Ipswich Town at Portman Road.
Crystal Palace will be hoping to pull clear of the bottom three with a win over Derby County.
Relegation threatened Sheffield United will play host to promotion chasing Leeds United in the early kickoff on Saturday.
The Blades are currently in the relegation zone six points adrift of safety, while Leeds currently occupy the playoff zone. Leeds are the Championship’s leading goal scorers, while the Blades have scored less than any team in the division.
Blades duo Darius Henderson and Lee Williamson are suspended, while Johnny Ertl is ruled out with a knee problem. Matt Lowton is an injury doubt, while Bjorn Helge Riise is set to return from a hamstring strain.
Defender Paul Connolly will return for Leeds after a long injury layoff, while captain Richard Naylor should also be fit to play.
Playoff chasing Burnley will continue their promotion challenge when they travel to face Bristol City on Saturday. Burnley are three points behind sixth placed Nottingham Forest with a game in hand, while Bristol are 10 points further back.
Burnley will be looking to extend a four game unbeaten run away from home, while Bristol will be looking for their third straight home win.
Defender Liam Fontaine looks set to miss out for an ankle injury for Bristol. Even if he manages to face Burnley, Fontaine is likely to undergo season ending surgery next week.
Dean Marney is doubtful for Burnley with a knee problem and will be assessed ahead of kickoff. Charlie Austin, Steven Thompson, Martin Paterson and Chris McCann are all ruled out with injury for the Clarets.
Cardiff City will continue their promotion challenge when they travel to face mid-table Millwall on Saturday. Cardiff are four points behind second placed Norwich City and will be looking to snap a three game winless skid. Millwall are seven points behind the playoff spots and will be looking for their third straight win.
Defender Darren Purse is back from suspension for Millwall, while striker Neil Harris will return from a hip injury. Midfielder Hameur Bouazza could also feature for the Lions after recovering from a knee problem.
Striker Michael Chopra is ruled out for Cardiff with a torn hamstring, while goalkeepers Tom Heaton and David Marshall remain sidelined with injury.
Rock bottom Preston North End will play host to Coventry City having snapped a 15 game winless streak in midweek. Preston’s 3-0 win at Scunthorpe United means they are now 10 points adrift of safety, while Coventry are eight points above the drop zone after a six game winless streak.
PNE have no fresh injury concerns, and manager Phil Brown looks set to field the same team that earned him his first win as manager in midweek.
Striker Marlon King is suspended for Coventry, while Martin Cranie is ruled out with a hamstring injury. Clive Platt and Lee Carsley are injury doubts and will be assessed ahead of kickoff.
Swansea City and Nottingham Forest will go head to head in a promotion battle at the Liberty Stadium. Third placed Swansea are three points behind the automatic promotion spots, while sixth placed Forest are three points further back.
Both teams will enter this game looking to regain their winning touch. Forest are without victory in their last six games, while Swansea are winless in three.
Striker Fabio Borini could make his Swansea debut after joining the club this week on loan from Chelsea. Captain Garry Monk and Andrea Orlandi could return from injury for the Swans.
Forest striker Robert Earnshaw has been ruled out for month with a hamstring injury, while Middlesbrough loanee Kris Boyd could make his full debut in the Forest attack.
League leading Queens Park Rangers will be looking to extend their seven point lead at the top of the table when they travel to face struggling Doncaster Rovers.
QPR have won four of their last five games, while Doncaster have slid to within 10 points of the relegation zone after one win on their last 10 fixtures.
John Oster and Neil Sullivan will return from injury for Rovers, while leading goal scorer Billy Sharp is out due to a groin problem. Joe Mills, James Chambers, James O’Connor and Mustapha Dumbaya will all be sidelined with injury for Doncaster.
Reading will be looking to extend a six game Championship unbeaten streak when they travel to face Barnsley on Saturday.
Reading are six points behind sixth placed Nottingham Forest with a game in hand, while Barnsley are a further seven points back.
Midfielder Hugo Colace could feature for Barnsley after along injury layoff that included rumors of him leaving the club. Jacob Mellis, Paul McShane and Jason Shackell are all injury doubts and will be assessed ahead of kickoff.
Reading’s Matt Mills is ruled out with injury along with Ivar Ingimarsson, Alex Pearce and Andy Griffin. Mikele Leigertwood, Noel Hunt and Jobi McAnuff are all doubtful and will be assessed ahead of kickoff.
Relegation threatened Scunthorpe United will be looking to avoid their fourth straight defeat when they travel to face Ipswich Town at Portman Road.
Scunthorpe currently occupy the relegation zone and are four points adrift of safety, while Ipswich are 12 points above the bottom three after a three game winless streak.
Ipswich captain David Norris is out with an ankle problem, while Mark Kennedy is a long-term injury absentee. Colin Healy could feature for the Tractor Boys after recovering from a stomach problem.
Sam Togwell and Ben Gordon will return from injury for Scunthorpe, while Andy Hughes could also be sidelined.
Leicester City and Portsmouth will go head to head with both teams looking for points to keep their playoff hopes alive. Leicester are five points behind sixth placed Nottingham Forest, while Portsmouth are four points further back.
Chelsea loanee Jeffrey Bruma could return for Leicester, while Steve Howard and Patrick van Aanholt are sidelined with injury for the Foxes.
Former Portsmouth striker Yakubu Ayegbini will lead the Leicester attack against a Pompey team that has kept clean sheets in seven of their last eight games.
Midfielder Liam Lawrence is doubtful for Portsmouth after aggravated a calf injury in training this week.
Playoff chasing Watford will be looking to extend a five game winning streak when they travel to face struggling Middlesbrough. Watford are currently four points behind the playoff spots, while Middlesbrough are seven points above the drop zone after going unbeaten in their last two games.
Defensive pair Stephen McManus and Andrew Davies are injury doubts for Middlesbrough, with Maximilian Haas and Jonathan Grounds being possible replacements.
Boro also have lack of attacking options with Leroy Lita injured and Kris Boyd and Lee Miller currently out on loan.
Middlesbrough fans will rue the fact that Championship leading goal scorer Danny Graham who will lead Watford’s attack is a graduate of the Middlesbrough youth academy, and left the club with few people noticing four years ago.
Defensive due Lloyd Doyley and Lee Hodson are injury doubts for Watford and will be assessed ahead of kickoff.
Crystal Palace will be hoping to pull clear of the relegation zone when they play host to Derby County on Saturday. Palace are currently four points clear of the bottom three, while Derby are five points further ahead after a morale boosting win over promotion chasing Swansea City last weekend.
Defender Claude Davis could start for Palace against his former club, while Paddy McCarthy (suspension) and Alex Marrow (injury) will miss out for the Eagles.
Tomasz Cywka is sidelined for Derby with a knee problem, while Jake Buxton (groin) and Shaun Deeney (shoulder) are also ruled out. Russell Anderson and James Bailey look set ot return to fitness for the Rams.
Second placed Norwich City will be looking to extend a seven game unbeaten streak when they travel to face Hull City on Saturday. Norwich are three points ahead of third placed Swansea City, while Hull are five points behind the playoff spots.
Defender Andy Dawson looks set to return for Hull, while Hope Akpan will make his Tigers debut after joining the club this week from Everton.
Chris Martin is ruled out with a hamstring injury for Norwich, while Aaron Wilbraham is doubtful with a back problem.
