The action kicks off on Friday with Inter Milan's clash versus Salernitana, but this round's two standout fixtures will take place during the weekend.

Matchday 28 in Serie A is here. The upcoming round in the Italian top-flight kicks off on Friday, with defending champions Inter Milan commencing the action with their 2:45 p.m. ET showdown with bottom-of-the-table Salernitana.

The weekend fixtures kick off with Udinese vs Sampdoria, but it is the Roma vs Atalanta clash that fans are looking forward to, as two teams chasing European football gear up for battle. The fun will carry on to Sunday, with the final fixture of this round being the standout game: Napoli vs AC Milan.

Who'll enjoy success on this matchday? Will this season's exciting Scudetto race take another twist? Which team will gain ground in the top-four chase? Here's everything you need to know about the upcoming fixtures.

Who are the top teams in Serie A ahead of Matchday 28?

Pos.SquadraPGVPSGFGSDRPtForma
1 Internazionale 35 28 5 2 81 19 +62 89 SVVPV
2 Milan 35 21 8 6 67 42 +25 71 PPSPV
3 Juventus 34 18 11 5 47 26 +21 65 PPPVS
4 Bologna 35 17 13 5 49 27 +22 64 PPVPP
5 Roma 34 17 8 9 61 41 +20 59 PVSVP
6 Atalanta 33 17 6 10 61 37 +24 57 VVPSV
7 Lazio 35 17 5 13 45 37 +8 56 PVVVS
8 Fiorentina 34 14 8 12 51 39 +12 50 SVVPS
9 Napoli 34 13 11 10 52 43 +9 50 PSPVS
10 Torino 35 11 14 10 31 31 0 47 PSPPS
11 Monza 35 11 12 12 38 46 -8 45 PPSPS
12 Genoa 35 10 13 12 41 43 -2 43 PVSPV
13 Lecce 35 8 13 14 32 50 -18 37 PPVVS
14 Hellas Verona 35 8 10 17 33 46 -13 34 VSVPS
15 Cagliari 35 7 12 16 37 60 -23 33 PSPPV
16 Frosinone 35 7 11 17 43 63 -20 32 PVPPP
17 Empoli 35 8 8 19 26 50 -24 32 PSVSV
18 Udinese 34 4 17 13 32 51 -19 29 PSSSP
19 Sassuolo 35 7 8 20 41 70 -29 29 VSSPP
20 Salernitana 34 2 9 23 26 73 -47 15 SSSPS

Champions League (fase a gironi)
Europa League (fase a gironi)
Promotion - Europa Conference League (Qualification: )
Relegation - Serie B

Top games to watch on Matchday 28 in Serie A

Roma vs Atalanta: This is one of the standout games as two teams hopeful of qualifying for Europe lock horns this weekend. Roma are sixth in the table, which would earn them a spot in the UEFA Europa Conference League, while Atalanta sit in fifth, which would secure them Europa League football. However, only three points separate these two teams, meaning Mourinho's side can go level with La Dea should they triumph. Fortunately, the Giallorossi enter this game on the back of their 1-0 triumph over Spezia, having gone four straight matches without a win in the build-up. The visitors, on the other hand, have only lost once in their last five outings, winning three while drawing one.

Juventus vs Spezia: Allegri's men went from being in danger of missing out on the top four to now being the favorites for the final UEFA Champions League spot. Juventus currently boast 50 points, but their grip isn't strong, as fifth-placed Atalanta are only three points behind while sixth-placed Roma trail by six. Next up for the Old Lady is Spezia, who are in the midst of a relegation battle. Given Dusan Vlahovic's sizzling hot form, the Bianconeri should enter this tie with confidence.

Napoli vs AC Milan: Given the current Serie A table, this game could be monumental in this season's title race. Napoli, who are first in the standings with 57 points, host second-placed AC Milan, who are also on 57 points, as both sides look to move clear at the top. Inter Milan, who are in action the day before, are only two points behind, meaning a draw could see both 

Gli Azzurri and the Rossoneri miss out on the top spot. Form has slipped away from both sides, but it is the hosts that head into this tie on the back of a victory, beating Lazio 2-1 to end their four-game winless run. Pioli's men, on the other hand, have drawn all of their last three outings, with their most recent being a Coppa Italia showdown with Inter. Who'll win Sunday's fixture? Don't miss this game. 

Here are a few more standout fixtures to watch in Serie A on Matchday 28

Serie A, Top 5 Fixtures, Matchday 28, AC Milan, Napoli, Inter Milan, Salernitana, Roma, Atalanta,  Cagliari, Lazio, Spezia, Juventus

Who's out for Matchday 28 in Serie A?

Napoli: Kevin Malcuit (injured)

Inter Milan: Nicolo Barella (suspended)

AC Milan: Simon Kjaer, Zlatan Ibrahimovic, and Aleessio Romagnoli (all injured)

Roma: Leonardo Spinazzola, Sergio Oliveira, and Felix Afena-Gyan (all injured)

Atalanta: Duvan Zapata, Josio Ilicic, and Bryan Cabezas (injured); Rafael Toloi (suspended)

Juventus: Leonardo Bonucci, Giorgio Chiellini, Denis Zakaria, Weston McKennie, Alex Sandro, and Federico Chiesa (all injured)

Full list of games for Matchday 28 in Serie A