FC Dallas will look to keep up their Western Conference title challenge when they play host to Chivas USA.
Dallas are currently six points behind the league leading Los Angeles Galaxy, while Chivas are eight points behind the playoff spots.
Star playmaker David Ferreira is a long term injury absentee for Dallas, while Edson Edward and Maykel Galindo are also sidelined. Central midfielder Daniel Hernandez is questionable with a knee injury.
Martin Chavez will feature in the Dallas attack after scoring two goals in a 2-2 draw with the New York Red Bulls last time out.
Veteran defender Jimmy Conrad and midfielder Ben Zemanski are doubtful for Chivas with concussion and an ankle injury respectively.
The Eastern Conference leading Philadelphia Union will play host to the Colorado Rapids on Friday night.
The Union will be hoping to pull ahead of the Columbus Crew and the New York Red Bulls, while the Rapids can move into the Western playoff spots with a victory.
Philadelphia will be looking to extend a five game unbeaten streak, while the Rapids have lost only one of their last five games.
Striker Levi Houapeu is listed as questionable for the Union, while in-form striker Carlos Ruiz will lead the Philadelphia attack. Veteran goal scorer Ruiz has netted three goals in his last four games.
Striker Conor Casey is ruled out for the Rapids, while Jamie Smith and Omar Cummings are expected to be fit for Colorado.
It will be top against bottom in the West on Saturday, when the first placed LA Galaxy travel to face last placed Vancouver Whitecaps FC.
Vancouver snapped a four game losing skid last time out with a 2-2 draw at the San Jose Earthquakes. The Galaxy will travel to Canada looking to extend a 13 game unbeaten streak.
Atiba Harris is out injured for Vancouver, while Omar Salgado is away playing for the USA U-17 national team. Jay DeMerit and John Thorrington are injury doubts and will be assessed ahead of kickoff.
Sean Alvarado, Leonardo and Donovan Ricketts are all out injured for LA, while David Beckham and Chris Birchall are suspended. Juan Pablo Angel, Chad Barrett and Landon Donovan are listed as questionable for the Galaxy.
Sporting Kansas City will be looking to extend their 12 game unbeaten streak when they play host to the New England Revolution on Saturday.
The Revolution will travel to Kansas City in poor form having won only one of their last 11 fixtures.
Davy Arnaud, Craig Rocastle and Konrad Warzycha are ruled out for Sporting, while Aurelien Collin is questionable with a back injury.
Kheli Dube is out injured for the Revolution, while Chris Tierney is suspended. Ryan Cochrane and Kevin Alston are injury doubts for New England.
The Houston Dynamo will be looking to extend their nine game unbeaten streak when they face Seattle Sounders FC in Texas.
Calen Carr is out injured for Houston due to a concussion, while Je-Vaughn Watson is suspended.
Jhon Kennedy Hurtado and Steve Zakuani are ruled out for Seattle, while midfielder Brad Evans is doubtful with a hamstring injury.
The Columbus Crew can move top of the Eastern Conference with a win at Real Salt Lake.
The Crew are currently behind the Eastern Conference leading New York Red Bulls on tie-breakers alone, but they face a difficult task as RSL are unbeaten in their previous seven games.
Javier Morales is ruled out for Salt Lake, while Paulo Jr. and Alvaro Saborio are injury doubts.
Tony Tchani, Josh Williams and Dilly Duka are sidelined with injury for Columbus, while goalkeeper William Hesmer is doubtful with a quad strain.
The San Jose Earthquakes and D.C. United will go head to head with both teams needing a win to revive their playoff hopes.
The Earthquakes are looking to end an eight game winless streak, while D.C. have won one of their last eight contests.
Andre Luiz and Ike Opara are ruled out for San Jose, while Brad Ring abd Bobby Burling are suspended. Steven Beitashour and Aan Gordon are struggling with injury and will be assessed ahead of kickoff.
Branko Boskovic and Devon McTavish are sidelined with injury for United, while Santino Quaranta and Jed Zayner are also unavailable. Star striker Charlie Davies is an injury doubt along with Josh Wolff.
Toronto FC will travel to face the Portland Timbers looking to avoid their fifth straight defeat. The hometown Timbers will be looking to rebound from their 1-0 defeat at the Columbus Crew last weekend.
Kevin Goldthwaite and Spencer Thompson are both ruled out with knee injuries for the Timbers.
Toronto will be without Elbekay Bouchiba and Adrian Cann, while Dicoy Williams, Leandre Griffit are also sidelined. Julian de Guzman and Terry Dunfield are injury doubts and will be assessed ahead of kickoff.
FC Dallas will look to keep up their Western Conference title challenge when they play host to Chivas USA.
Dallas are currently six points behind the league leading Los Angeles Galaxy, while Chivas are eight points behind the playoff spots.
Star playmaker David Ferreira is a long term injury absentee for Dallas, while Edson Edward and Maykel Galindo are also sidelined. Central midfielder Daniel Hernandez is questionable with a knee injury.
Martin Chavez will feature in the Dallas attack after scoring two goals in a 2-2 draw with the New York Red Bulls last time out.
Veteran defender Jimmy Conrad and midfielder Ben Zemanski are doubtful for Chivas with concussion and an ankle injury respectively.
Star playmaker David Ferreira is a long term injury absentee for Dallas, while Edson Edward and Maykel Galindo are also sidelined. Central midfielder Daniel Hernandez is questionable with a knee injury.
Martin Chavez will feature in the Dallas attack after scoring two goals in a 2-2 draw with the New York Red Bulls last time out.
Veteran defender Jimmy Conrad and midfielder Ben Zemanski are doubtful for Chivas with concussion and an ankle injury respectively.
The Eastern Conference leading Philadelphia Union will play host to the Colorado Rapids on Friday night.
The Union will be hoping to pull ahead of the Columbus Crew and the New York Red Bulls, while the Rapids can move into the Western playoff spots with a victory.
Philadelphia will be looking to extend a five game unbeaten streak, while the Rapids have lost only one of their last five games.
Striker Levi Houapeu is listed as questionable for the Union, while in-form striker Carlos Ruiz will lead the Philadelphia attack. Veteran goal scorer Ruiz has netted three goals in his last four games.
Striker Conor Casey is ruled out for the Rapids, while Jamie Smith and Omar Cummings are expected to be fit for Colorado.
It will be top against bottom in the West on Saturday, when the first placed LA Galaxy travel to face last placed Vancouver Whitecaps FC.
Vancouver snapped a four game losing skid last time out with a 2-2 draw at the San Jose Earthquakes. The Galaxy will travel to Canada looking to extend a 13 game unbeaten streak.
Atiba Harris is out injured for Vancouver, while Omar Salgado is away playing for the USA U-17 national team. Jay DeMerit and John Thorrington are injury doubts and will be assessed ahead of kickoff.
Sean Alvarado, Leonardo and Donovan Ricketts are all out injured for LA, while David Beckham and Chris Birchall are suspended. Juan Pablo Angel, Chad Barrett and Landon Donovan are listed as questionable for the Galaxy.
Sporting Kansas City will be looking to extend their 12 game unbeaten streak when they play host to the New England Revolution on Saturday.
The Revolution will travel to Kansas City in poor form having won only one of their last 11 fixtures.
Davy Arnaud, Craig Rocastle and Konrad Warzycha are ruled out for Sporting, while Aurelien Collin is questionable with a back injury.
Kheli Dube is out injured for the Revolution, while Chris Tierney is suspended. Ryan Cochrane and Kevin Alston are injury doubts for New England.
The Houston Dynamo will be looking to extend their nine game unbeaten streak when they face Seattle Sounders FC in Texas.
Calen Carr is out injured for Houston due to a concussion, while Je-Vaughn Watson is suspended.
Jhon Kennedy Hurtado and Steve Zakuani are ruled out for Seattle, while midfielder Brad Evans is doubtful with a hamstring injury.
The Columbus Crew can move top of the Eastern Conference with a win at Real Salt Lake.
The Crew are currently behind the Eastern Conference leading New York Red Bulls on tie-breakers alone, but they face a difficult task as RSL are unbeaten in their previous seven games.
Javier Morales is ruled out for Salt Lake, while Paulo Jr. and Alvaro Saborio are injury doubts.
Tony Tchani, Josh Williams and Dilly Duka are sidelined with injury for Columbus, while goalkeeper William Hesmer is doubtful with a quad strain.
The San Jose Earthquakes and D.C. United will go head to head with both teams needing a win to revive their playoff hopes.
The Earthquakes are looking to end an eight game winless streak, while D.C. have won one of their last eight contests.
Andre Luiz and Ike Opara are ruled out for San Jose, while Brad Ring abd Bobby Burling are suspended. Steven Beitashour and Aan Gordon are struggling with injury and will be assessed ahead of kickoff.
Branko Boskovic and Devon McTavish are sidelined with injury for United, while Santino Quaranta and Jed Zayner are also unavailable. Star striker Charlie Davies is an injury doubt along with Josh Wolff.
Toronto FC will travel to face the Portland Timbers looking to avoid their fifth straight defeat. The hometown Timbers will be looking to rebound from their 1-0 defeat at the Columbus Crew last weekend.
Kevin Goldthwaite and Spencer Thompson are both ruled out with knee injuries for the Timbers.
Toronto will be without Elbekay Bouchiba and Adrian Cann, while Dicoy Williams, Leandre Griffit are also sidelined. Julian de Guzman and Terry Dunfield are injury doubts and will be assessed ahead of kickoff.
FC Dallas will look to keep up their Western Conference title challenge when they play host to Chivas USA.
Dallas are currently six points behind the league leading Los Angeles Galaxy, while Chivas are eight points behind the playoff spots.
Star playmaker David Ferreira is a long term injury absentee for Dallas, while Edson Edward and Maykel Galindo are also sidelined. Central midfielder Daniel Hernandez is questionable with a knee injury.
Martin Chavez will feature in the Dallas attack after scoring two goals in a 2-2 draw with the New York Red Bulls last time out.
Veteran defender Jimmy Conrad and midfielder Ben Zemanski are doubtful for Chivas with concussion and an ankle injury respectively.
