Despite Bastian Schweinsteiger, Sami Khedira, and Mario Gomez missing this crucial clash due to injuries, the Bayern Munich player is confident his team will book a ticket to the final.
Speaking at a general press conference, the 26-year-old attacking midfielder said:
"Fear never comes into it.
"We know France have many good players, but Iceland didn't honestly look that good at the back so if we defend well as a team, we will not let these players get into positions to show their class.
"We're respectful, but I'm optimistic we'll find a solution even if we've got some players missing out, which is bitter.
"This happens in football; there are always injuries and suspensions for big games but you've got to compensate as a team.
"I said before the tournament that I've never seen so much depth of quality in our team as we have now so I'm sure we can compensate."
Muller added:
"France have not got here by luck.
"But they are now under a bit of pressure too as the hosts, and they know they're facing a strong Germany side.
"We were both being mentioned as favourites before the tournament, and there aren't many bigger games than this one."
Thomas Muller has appeared in all of Germany's UEFA Euro 2016 matches but has yet to score.
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