Two teams have sealed their spot in the next round, and there could be at least two more added to that list. Follow this week's game with this guide.

With only two games left for each team in the Group Stage, teams playing in the Copa Libertadores will want to seal their spots in the next round before things get out of hand for Matchday 6. Palmeiras and Atlético Mineiro are the only teams with a ticket for the next round, but quite a few more could seal their spot in the KO stage with wins or even draws here.

Before we have a deeper look at what will be in store for us this week, we should have a look at the state of each group.

Group A has already been won by Palmeiras, but the fight for the second spot is very much alive between Defensa y Justicia, Independiente del Valle, and Universitario. As for Group B, all teams have a fighting chance of making it to the next round, as every club has won two games with only four matches left in the group.

Barcelona wasted a big chance to win Group C last week, and now, the team from Ecuador will have to beware about another loss against Boca Juniors. Elsewhere, Santos face The Strongest with all to play for in the group. The same goes for Group D, where Fluminense are one win away from securing their spot in the next round, but River, Junior, and even Santa Fe still have a legitimate chance of finishing second.

Sao Paulo saw Racing getting level with them in Group E, and now both teams will lock horns with the top spot in the group up for grabs. Whichever team loses will have to be wary of Rentistas' performance, as the Uruguayan side may still have a say in the group if they can find a way to beat Sporting Cristal. As for Group F, Argentinos Juniors saw their unbeaten run come to an end last week, but their are still in the driver's seat over Universidad Católica and Atlético Nacional.

Flamengo are one point away from reaching the next round, and they will try to secure that spot with a win over Liga de Quito, with Vélez keeping a close eye on their game. Meanwhile, Atlético Mineiro will try to extend their dominance in Group H, where they secured their spot in the next round last week. In that group, Cerro Porteño and Deportivo La Guaira are still in contention, while América de Cali may need more than a miracle to earn a spot in the next round.

Matchday 5 will kick off with a bang as six games are scheduled for Tuesday. Out of that bunch, the clash between Sao Paulo and Racing will be the one to watch. Another interesting match will see Palmeiras and Defensa y Justicia going at it that day.

Wednesday will also give fans quite a few thrills, with seven games coming their way. Out of those, fans should really pay attention to the Flamengo vs Liga de Quito game and the River Plate vs Junior showdown.

Last, but not least, there will be three matches being played on Thursday, with the one between Boca Juniors and Barcelona being the most attractive one.

Here's the full schedule for Matchday 5 in the 2021 Copa Libertadores.

Tuesday, 18 May
Live
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6:15pm
Nacional 1 - 0 Universidad Católica
Live
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6:15pm
Palmeiras 3 - 4 Defensa y Justicia
Live
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6:15pm
The Strongest 2 - 1 Santos
Live
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8:30pm
Fluminense 1 - 2 Junior
Live
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8:30pm
São Paulo 0 - 1 Racing Club
Live
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8:30pm
Universitario 3 - 2 Independiente del Valle
Wednesday, 19 May
Live
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6:00pm
Sporting Cristal 2 - 0 Rentistas
Live
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6:00pm
Vélez Sarsfield 2 - 1 Unión La Calera
Live
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8:00pm
Cerro Porteño 0 - 1 Atlético Mineiro
Live
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8:00pm
Flamengo 2 - 2 LDU Quito
Live
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8:00pm
River Plate 2 - 1 Santa Fe
Live
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10:00pm
América de Cali 3 - 1 Deportivo La Guaira
Live
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10:00pm
Deportivo Táchira 7 - 2 Always Ready
Thursday, 20 May
Live
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6:00pm
Argentinos Juniors 1 - 0 Atlético Nacional
Live
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8:00pm
Boca Juniors 0 - 0 Barcelona