Real Sociedad will head into the Camp Nou facing a difficult challenge. The Txuri-Urdin are coming off a four goal thumping at the Vicente Calderon against Atletico Madrid, with put the Madrid side at the top of the La Liga table.
The hosts will be equally frustrated on Wednesday, after their disappointing performance at the weekend.
Playing at home is normally a very good chance for the Blaugrana to win, but Valencia had other ideas. Los Che scored three goals, more than any other team has scored at the Camp Nou this season, and defeated Tata Martino's squad.
That was Barcelona's first defeat at home in the league, which will leave them disappointed. A meeting with Real Sociedad who they defeated 4-1 earlier in the season should give them a good chance to get back to winning ways.
Tata Martino wants his side to bounce back from their latest defeat, avoiding any possible talks of a crisis.
"It is true that crises always have a beginning so it's up to us to cut it short," said the Barcelona manager.
"We have it within our power this does not go any further."
Martino will welcome Carles Puyol, Martin Montoya, Ibrahim Afellay and Isaac Cuenca into his 22-player squad for Wednesday's match, after they all missed the match against Valencia.
Sociedad will have to be cautious knowing that the hosts will be wanting to bounce back after their last match. Knowing that the second leg is at the Anoeta Stadium, keeping Wednesday's match close is a must.
The visitors have not won at Camp Nou since the 1990/91 season, and they have not progressed to the Copa del Rey Final since 1998, when they were defeated 1-0 by Barcelona. Without Esteban Graneiro (knee), Alberto de la Bella (ankle/foot) and Dani Estrada (thigh), Jagoba Arrasate will try to lead his squad to their third Copa del Rey victory since he took over the club in July of 2013.
Watch Barcelona vs Real Sociedad live on Wednesday, January 5, 2014:
In Canada at 16:00 ET on: beIN Sports Play Canada