Matchday 6 of the Premier League promises to bring emotions to all fans around the world. With Chelsea and Liverpool will have to work extra time to keep their players fit after a busy week in European competitions, which means that both West Ham and Southampton will try to take advantage of their tired legs.
After being shocked by Lyon in the UEFA Champions League, Manchester City will not be allowed any distractions when they visit Cardiff, while fourth-placed Watford will try to get back to winning ways when they visit Fulham.
Match of the Week - Manchester United vs Wolverhampton Wanderers
The first meeting between these teams in over six years will have an interesting ingredient, as Jose Mourinho and Nuno Espiritu Santo face each other in an all-Portuguese-coach matchup. The visitors' good form in their return to the English top flight will try to see them earn their first victory at Old Trafford in the 21st Century. On the other hand, José Mourinho will try to avoid back-to-back losses at home for the first time in his career.
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Talk of the weekend - Will Chelsea and Liverpool keep their flawless run?
Both teams walked away with narrow wins from their European clashes this week. Added to that, Chelsea will have to endure their back-and-forth trip to Greece, which will certainly complicate things a bit for Maurizio Sarri's men.
Major absences and returns
Absences
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Tottenham: Hugo Lloris, Dele Alli, Moussa Sissoko (injuries).
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Liverpool: Alex Oxlade-Chamberlain, Adam Lallana (injuries)
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Manchester Utd: Phil Jones, Ander Herrera (injuries), Marcus Rashford (suspended), Nemanja Matic (suspended).
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Chelsea: Mateo Kovacic, Pedro (injuries)
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West Ham: Chicharito (illness), Jack Wilshere, Andy Carroll, Marko Arnautovic (injuries)
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Leicester City: Wes Morgan (suspended)
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Manchester City: Kevin de Bruyne, Benjamin Mendy, Eliaquim Mangala, Danilo (injuries)
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Arsenal: Lucas Torreira, Sead Kolasinac, Carl Jenkinson (injuries)
Returns
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Liverpool: Dejan Lovren (returns from injury)
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Chelsea: Cesc Fábgregas (returns from injury)
Kick-off time, date, and broadcast channels of other EPL Matchday 5 fixtures
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Cardiff City 0 - 5 Manchester City
September 22, 2018 10:00amCardiff City Stadium (Cardiff (Caerdydd))This match has ended. Below are the original Live broadcast details for this match.
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Leicester City 3 - 1 Huddersfield Town
September 22, 2018 10:00amKing Power Stadium (Leicester, Leicestershire)This match has ended. Below are the original Live broadcast details for this match.
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Brighton & Hove Albion 1 - 2 Tottenham Hotspur
September 22, 2018 12:30pmThe American Express Community Stadium (Falmer, East Sussex)This match has ended. Below are the original Live broadcast details for this match.
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